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Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases

Biochimica et Biophysica Acta (BBA) - Biomembranes · 1993 · Vol. 1151(2) · pp. 201–215
Gilad HaranRivka CohenLiliana K. BarYechezkel Barenholz
Lipid Membrane Structure and BehaviorNanoparticle-Based Drug DeliveryMolecular Sensors and Ion DetectionLiposomeChemistryAmmonium sulfateWeak baseAmphiphileAqueous solutionAqueous two-phase systemChromatographyAmmoniumIonic strength

MeSH terms

AmmoniaAmmonium SulfateDoxorubicinDrug StabilityElectric ConductivityHydrogen-Ion ConcentrationLiposomesQuality ControlTechnology, Pharmaceutical1,2-Dipalmitoylphosphatidylcholine
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References
Phosphorus Assay in Column Chromatography
Journal of Biological Chemistry · 1959 · 12,851 citations
Vesicles of variable sizes produced by a rapid extrusion procedure
Biochimica et Biophysica Acta (BBA) - Biomembranes · 1986 · 1,680 citations
Liposomes as drug carriers
Life Sciences · 1977 · 654 citations
Phase equilibria in the phosphatidylcholine-cholesterol system
Biochimica et Biophysica Acta (BBA) - Biomembranes · 1987 · 1,052 citations
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