reviewTop 10% cited
Meta-analysis of low molecular weight heparin in the prevention of venous thromboembolism in general surgery
British journal of surgery · 2001 · Vol. 88(7) · pp. 913–930
Patrick Mismetti✉(Thrombosis Research Institute)Silvy Laporte(Thrombosis Research Institute)J-Y Darmon(Northridge Hospital Medical Center)Andréa Buchmuller(Thrombosis Research Institute)H Decousus(Thrombosis Research Institute)
Abstract
Asymptomatic DVT may be regarded as a reliable surrogate endpoint for clinical outcome in studies investigating thromboprophylaxis in general surgery. LMWH seems to be as effective and safe as UFH. Determination of the optimal dose regimen of LMWH for this indication requires further investigation.
Venous Thromboembolism Diagnosis and ManagementAtrial Fibrillation Management and OutcomesCentral Venous Catheters and HemodialysisMedicinePulmonary embolismDeep veinRelative riskSurgeryLow molecular weight heparinPlaceboHeparinThrombosisAsymptomatic
MeSH terms
AnticoagulantsHeparin, Low-Molecular-WeightHumansThromboembolismRandomized Controlled Trials as TopicVenous Thrombosis
Citations
646
FWCI
7.58
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References
110
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98%
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References
Prevention of Venous Thromboembolism
CHEST Journal · 2001 · 4,396 citations
Heparin and Low-Molecular-Weight Heparin Mechanisms of Action, Pharmacokinetics, Dosing, Monitoring, Efficacy, and Safety
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Antithrombotic Therapy for Venous Thromboembolic Disease
CHEST Journal · 2001 · 2,050 citations
Prevention of Venous Thromboembolism in Internal Medicine with Unfractionated or Low-molecular-weight Heparins: A Meta-analysis of Randomised Clinical Trials
Thrombosis and Haemostasis · 2000 · 381 citations
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