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A New Property of MCM-41: Drug Delivery System

Chemistry of Materials · 2000 · Vol. 13(2) · pp. 308–311

María Vallet‐Regí✉(Universidad Complutense de Madrid)A. Rámila(Universidad Complutense de Madrid)R. P. del Real(Universidad Complutense de Madrid)Joaquı́n Pérez-Pariente(Universidad Complutense de Madrid)

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Abstract

A new application of MCM-41 mesoporous materials has been developed. Two kinds of surfactants, C16TAB and C12TAB, have been employed to get different pore sizes. The samples were disk-shaped conformed before and after charging with ibuprofen, an anti-inflammatory drug. In all the cases the weight percent ratio of drug/MCM-41 was 30%. The drug release plots show a different behavior depending on the method for charging the drug in the material but not on the employed surfactant.

Mesoporous Materials and Catalysis Aerogels and thermal insulation Nanoparticle-Based Drug DeliveryDrugIbuprofenDrug deliveryPulmonary surfactantMCM-41Mesoporous materialMaterials scienceChemical engineeringNanotechnologyChromatography

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