article Open AccessTop 1% cited
the Incidence and Risk Factors of Hepatocellular Carcinoma in Patients With Nonalcoholic Steatohepatitis
Hepatology · 2010 · Vol. 51(6) · pp. 1972–1978
Mustafa Ascha(Cleveland Clinic)Ibrahim A. Hanouneh(Cleveland Clinic)Rocío López(Cleveland Clinic)Tarek Tamimi(Cleveland Clinic)Ariel Feldstein(Cleveland Clinic)Nizar N. Zein✉(Cleveland Clinic)
Abstract
Patients with NASH cirrhosis have a greatly increased risk of liver cancer. Alcohol consumption, a modifiable risk factor, appears to be the most significant factor associated with risk of HCC development in our study population.
Liver Disease Diagnosis and TreatmentHepatocellular Carcinoma Treatment and PrognosisLiver Disease and TransplantationMedicineCirrhosisHepatocellular carcinomaInternal medicineGastroenterologyIncidence (geometry)Cumulative incidenceHepatologyCohort
MeSH terms
Alcohol DrinkingFatty LiverFemaleHepatitis CCarcinoma, HepatocellularHumansLiver CirrhosisLiver NeoplasmsMaleMiddle AgedRetrospective StudiesRisk FactorsUnited StatesIncidence
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1,287
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38
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References
Cryptogenic Cirrhosis: Clinical Characterization and Risk Factors for Underlying Disease
Hepatology · 1999 · 1,133 citations
Expanding the natural history of nonalcoholic steatohepatitis: From cryptogenic cirrhosis to hepatocellular carcinoma
Gastroenterology · 2002 · 1,434 citations
Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
Gastroenterology · 2007 · 5,410 citations
Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults
New England Journal of Medicine · 2003 · 7,697 citations
Management of Hepatocellular Carcinoma *
Hepatology · 2005 · 5,870 citations
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