reviewTop 10% cited

Choosing between glycolysis and oxidative phosphorylation: A tumor's dilemma?

Biochimica et Biophysica Acta (BBA) - Bioenergetics · 2010 · Vol. 1807(6) · pp. 552–561

Caroline José(Université de Bordeaux)Nadège Bellancé(Université de Bordeaux)Rodrigue Rossignol✉(Université de Bordeaux)

Cancer, Hypoxia, and Metabolism Mitochondrial Function and Pathology ATP Synthase and ATPases ResearchOxidative phosphorylationDilemmaGlycolysisPhosphorylationChemistryCell biologyCancer researchBiochemistryMetabolismBiology

MeSH terms

AnimalsEnergy MetabolismGlycolysisHumansMitochondriaModels, BiologicalNeoplasmsOxidative PhosphorylationCell RespirationMetabolic Networks and Pathways

Funding

Cancéropôle Grand Ouest

Citations

505

FWCI

7.40

field-weighted impact

References

127

Percentile

97%

vs. same field & year

Citations per year

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References

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HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia

Cell Metabolism · 2006 · 3,827 citations

The Hallmarks of Cancer

Cell · 2000 · 28,385 citations

Akt Stimulates Aerobic Glycolysis in Cancer Cells

Cancer Research · 2004 · 1,453 citations

Why do cancers have high aerobic glycolysis?

Nature reviews. Cancer · 2004 · 4,733 citations

Accumulation of Krebs cycle intermediates and over-expression of HIF1α in tumours which result from germline FH and SDH mutations

Human Molecular Genetics · 2005 · 844 citations

Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

Cancer Cell · 2006 · 1,584 citations

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