review Open AccessTop 10% cited
The human leukemia cell line, THP-1: A multifacetted model for the study of monocyte-macrophage differentiation
Cellular and Molecular Life Sciences · 1991 · Vol. 47(1) · pp. 22–31
Johan Auwerx✉(KU Leuven)
Immune cells in cancerPhagocytosis and Immune RegulationInvertebrate Immune Response MechanismsTHP1 cell lineMonocyteCell cultureMonocytic leukemiaU937 cellMacrophageAcute monocytic leukemiaCell biologyCellular differentiationMyeloid leukemia
MeSH terms
Cell DifferentiationCell LineHumansLeukemia, Monocytic, AcuteMacrophagesModels, BiologicalMonocytesProto-OncogenesGene Expression
Citations
814
FWCI
3.34
field-weighted impact
References
120
Percentile
93%
vs. same field & year
Citations per year
Cited by
The use of THP-1 cells as a model for mimicking the function and regulation of monocytes and macrophages in the vasculature
Atherosclerosis · 2011 · 383 citations
References
Biology of interleukin 1
The FASEB Journal · 1988 · 1,538 citations
Secretory products of macrophages.
Journal of Clinical Investigation · 1987 · 2,642 citations
Establishment and characterization of a human acute monocytic leukemia cell line (THP‐1)
International Journal of Cancer · 1980 · 2,241 citations
The Cell Biology of Macrophage Activation
Annual Review of Immunology · 1984 · 1,612 citations
LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in Atherosclerosis
Annual Review of Biochemistry · 1983 · 2,304 citations
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Establishment and characterization of a human acute monocytic leukemia cell line (THP‐1)
International Journal of Cancer · 1980 · 2,241 citations
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