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Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide

Cell stem cell · 2008 · Vol. 2(2) · pp. 141–150

Guangwen RenLiying ZhangXin ZhaoGuangwu XuYingyu ZhangArthur I. RobertsRobert Chunhua Zhao(Chinese Academy of Medical Sciences & Peking Union Medical College)Yufang Shi✉

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Mesenchymal stem cell research Tissue Engineering and Regenerative Medicine MicroRNA in disease regulationBiologyMesenchymal stem cellNitric oxideImmunosuppressionCell biologyChemokineStem cellImmunologyAction (physics)Cell

MeSH terms

Interferon gamma ReceptorAnimalsCell MovementCells, CulturedGraft vs Host DiseaseHypersensitivity, DelayedImmune ToleranceInterferon-gammaNitric OxideCytokinesReceptors, InterferonMice, KnockoutChemokinesMiceNitric Oxide Synthase Type II

Funding

National Space Biomedical Research Institute

Citations

2,113

FWCI

35.77

field-weighted impact

References

Percentile

100%

vs. same field & year

Citations per year

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References

Concise Review: Mesenchymal Stem Cells: Their Phenotype, Differentiation Capacity, Immunological Features, and Potential for Homing

Stem Cells · 2007 · 2,356 citations

Human Bone Marrow Stromal Cells Express a Distinct Set of Biologically Functional Chemokine Receptors

Stem Cells · 2005 · 719 citations

Mesenchymal stem cells inhibit lymphocyte proliferation by mitogens and alloantigens by different mechanisms

Experimental Cell Research · 2005 · 495 citations

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Stem Cells · 2005 · 1,312 citations

Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase–mediated tryptophan degradation

Blood · 2004 · 1,627 citations

Human mesenchymal stem cells modulate allogeneic immune cell responses

Blood · 2004 · 4,508 citations

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