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Larynx Preservation in Pyriform Sinus Cancer: Preliminary Results of a European Organization for Research and Treatment of Cancer Phase III Trial
JNCI Journal of the National Cancer Institute · 1996 · Vol. 88(13) · pp. 890–899
J.-L. Lefebvre✉(Centre Oscar Lambret)Dominique Chevalier(Hôpital Claude Huriez)B Luboïnski(Institut Gustave Roussy)A. Kirkpatrick(European Organisation for Research and Treatment of Cancer)Laurence Collette(European Organisation for Research and Treatment of Cancer)Tarek Sahmoud(European Organisation for Research and Treatment of Cancer)
Abstract
Larynx preservation without jeopardizing survival appears feasible in patients with cancer of the hypopharynx. On the basis of these observations, the EORTC has now accepted the use of induction chemotherapy followed by radiation as the new standard treatment in its future phase III larynx preservation trials.
Head and Neck Cancer StudiesHead and Neck Surgical OncologySalivary Gland Tumors Diagnosis and TreatmentMedicineLaryngectomySurgeryRadiation therapyLarynxInduction chemotherapyCancerChemotherapyNeck dissectionPyriform Sinus
MeSH terms
AdultAgedAntineoplastic Combined Chemotherapy ProtocolsCarcinoma, Squamous CellCombined Modality TherapyEuropeFemaleHumansHypopharyngeal NeoplasmsLaryngectomyMaleMiddle AgedPharyngectomyProspective StudiesRadiotherapy Dosage
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References
Sequential Treatment Assignment with Balancing for Prognostic Factors in the Controlled Clinical Trial
Biometrics · 1975 · 2,349 citations
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Biometrics · 1979 · 3,326 citations
Nonparametric Estimation from Incomplete Observations
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