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Larynx Preservation in Pyriform Sinus Cancer: Preliminary Results of a European Organization for Research and Treatment of Cancer Phase III Trial

JNCI Journal of the National Cancer Institute · 1996 · Vol. 88(13) · pp. 890–899
J.-L. LefebvreDominique ChevalierB LuboïnskiA. KirkpatrickLaurence ColletteTarek Sahmoud

Abstract

Larynx preservation without jeopardizing survival appears feasible in patients with cancer of the hypopharynx. On the basis of these observations, the EORTC has now accepted the use of induction chemotherapy followed by radiation as the new standard treatment in its future phase III larynx preservation trials.

Head and Neck Cancer StudiesHead and Neck Surgical OncologySalivary Gland Tumors Diagnosis and TreatmentMedicineLaryngectomySurgeryRadiation therapyLarynxInduction chemotherapyCancerChemotherapyNeck dissectionPyriform Sinus

MeSH terms

AdultAgedAntineoplastic Combined Chemotherapy ProtocolsCarcinoma, Squamous CellCombined Modality TherapyEuropeFemaleHumansHypopharyngeal NeoplasmsLaryngectomyMaleMiddle AgedPharyngectomyProspective StudiesRadiotherapy Dosage
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References
A Multiple Testing Procedure for Clinical Trials
Biometrics · 1979 · 3,326 citations
Nonparametric Estimation from Incomplete Observations
Journal of the American Statistical Association · 1958 · 38,793 citations
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