article Open AccessTop 1% cited
Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis
American Journal Of Pathology · 2009 · Vol. 176(1) · pp. 85–97
Benjamin D. Humphreys(Brigham and Women's Hospital)Shuei‐Liong Lin(Brigham and Women's Hospital)Akio Kobayashi(Harvard University)Thomas E. Hudson(Brigham and Women's Hospital)Brian T. Nowlin(Brigham and Women's Hospital)Joseph V. Bonventre(Brigham and Women's Hospital)M. Todd Valerius(Harvard University)Andrew P. McMahon(Harvard University)Jeremy S. Duffield✉(Brigham and Women's Hospital)
Renal and related cancersChronic Kidney Disease and DiabetesRenal cell carcinoma treatmentMyofibroblastFibrosisPathologyPericyteKidneyBiologyMedicineGenetics
MeSH terms
S100 Calcium-Binding Protein A4ActinsAnimalsCell MovementCells, CulturedDisease Models, AnimalEpithelial CellsFibroblastsFibrosisKidneyKidney TubulesMesodermS100 ProteinsPromoter Regions, GeneticTranscription Factors
Funding
- American Society of Nephrology
- Massachusetts General Hospital
- National Science Council
- National Institutes of Health
- Harvard Stem Cell Institute
Citations
1,398
FWCI
33.08
field-weighted impact
References
66
Percentile
100%
vs. same field & year
Citations per year
Cited by
The myofibroblast matrix: implications for tissue repair and fibrosis
The Journal of Pathology · 2012 · 753 citations
The proximal tubule is the primary target of injury and progression of kidney disease: role of the glomerulotubular junction
American Journal of Physiology-Renal Physiology · 2016 · 474 citations
Cardiac Fibrosis
Circulation Research · 2016 · 1,522 citations
Endothelial to Mesenchymal Transition (EndoMT) in the Pathogenesis of Human Fibrotic Diseases
Journal of Clinical Medicine · 2016 · 271 citations
Role of EMT in Metastasis and Therapy Resistance
Journal of Clinical Medicine · 2016 · 489 citations
Epithelial-mesenchymal transition in tissue repair and fibrosis
Cell and Tissue Research · 2016 · 565 citations
Redefining the In Vivo Origin of Metanephric Nephron Progenitors Enables Generation of Complex Kidney Structures from Pluripotent Stem Cells
Cell stem cell · 2013 · 851 citations
Perivascular Gli1+ Progenitors Are Key Contributors to Injury-Induced Organ Fibrosis
Cell stem cell · 2014 · 919 citations
References
Six2 Defines and Regulates a Multipotent Self-Renewing Nephron Progenitor Population throughout Mammalian Kidney Development
Cell stem cell · 2008 · 962 citations
Intrinsic Epithelial Cells Repair the Kidney after Injury
Cell stem cell · 2008 · 861 citations
Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-Producing Cells in Obstructive Fibrosis of the Kidney
American Journal Of Pathology · 2008 · 834 citations
Epithelial-mesenchymal transition and its implications for fibrosis
Journal of Clinical Investigation · 2003 · 2,289 citations
TGF-β and epithelial-to-mesenchymal transitions
Oncogene · 2005 · 1,577 citations
Evidence that fibroblasts derive from epithelium during tissue fibrosis
Journal of Clinical Investigation · 2002 · 1,813 citations
A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs
Cell stem cell · 2008 · 3,949 citations
Fibroblasts in Kidney Fibrosis Emerge via Endothelial-to-Mesenchymal Transition
Journal of the American Society of Nephrology · 2008 · 853 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.