article Open AccessTop 10% cited

Comparative Affinity of Duloxetine and Venlafaxine for Serotonin and Norepinephrine Transporters in vitro and in vivo, Human Serotonin Receptor Subtypes, and Other Neuronal Receptors

Neuropsychopharmacology · 2001 · Vol. 25(6) · pp. 871–880

Frank P. Bymaster✉(Eli Lilly (United States))

Neurotransmitter Receptor Influence on Behavior Receptor Mechanisms and Signaling Neuroscience and Neuropharmacology ResearchDuloxetineVenlafaxineSerotoninReuptake inhibitorSerotonin transporterPharmacologyIn vivoChemistryReuptakeSerotonin Plasma Membrane Transport Proteins

MeSH terms

Duloxetine HydrochlorideVenlafaxine HydrochlorideAnimalsCarrier ProteinsCell LineCyclohexanolsDose-Response Relationship, DrugHumansMaleMembrane GlycoproteinsMonoamine OxidaseNerve Tissue ProteinsNeuronsp-ChloroamphetamineRadioligand Assay

Citations

715

FWCI

5.99

field-weighted impact

References

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98%

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References

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Selective serotonin reuptake inhibitors versus tricyclic antidepressants: a meta-analysis of efficacy and tolerability

Journal of Affective Disorders · 2000 · 936 citations

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