reviewTop 1% cited

Peroxynitrite: biochemistry, pathophysiology and development of therapeutics

Nature Reviews Drug Discovery · 2007 · Vol. 6(8) · pp. 662–680

Csaba Szabó✉Harry Ischiropoulos(University of Pennsylvania)Rafael Radí✉(Universidad de la República)

Nitric Oxide and Endothelin Effects Neutrophil, Myeloperoxidase and Oxidative Mechanisms Electron Spin Resonance StudiesPeroxynitriteNitric oxidePeroxynitrous acidChemistrySuperoxidePharmacologyNeurodegenerationPathophysiologyInflammationNitric oxide synthase

MeSH terms

AnimalsCardiovascular DiseasesHumansMetalloporphyrinsModels, BiologicalMolecular StructureApoptosisNeurodegenerative DiseasesPeroxynitrous Acid

Funding

Universidad de la República Uruguay
National Institutes of Health

Citations

2,074

FWCI

48.26

field-weighted impact

References

321

Percentile

100%

vs. same field & year

Citations per year

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References

Peroxynitrite oxidation of sulfhydryls.

Journal of Biological Chemistry · 1991 · 2,480 citations

Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide

Archives of Biochemistry and Biophysics · 1991 · 2,199 citations

Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase

Archives of Biochemistry and Biophysics · 1992 · 1,496 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

Proceedings of the National Academy of Sciences · 1990 · 7,036 citations

Oxidative and nitrosative stress in acute renal ischemia

American Journal of Physiology-Renal Physiology · 2001 · 337 citations

Peroxiredoxins: A historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling

Free Radical Biology and Medicine · 2005 · 1,394 citations

Inhibition of Mitochondrial Electron Transport by Peroxynitrite

Archives of Biochemistry and Biophysics · 1994 · 692 citations

Nitric Oxide and Peroxynitrite in Health and Disease

Physiological Reviews · 2007 · 6,199 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

Proceedings of the National Academy of Sciences · 1990 · 7,036 citations

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