article Open AccessTop 1% cited
Induction and Activation of the Transcription Factor NFATc1 (NFAT2) Integrate RANKL Signaling in Terminal Differentiation of Osteoclasts
Developmental Cell · 2002 · Vol. 3(6) · pp. 889–901
Hiroshi Takayanagi(The University of Tokyo)Sunhwa Kim(The University of Tokyo)Takako Koga(Japan Science and Technology Agency)Hiroshi Nishina(The University of Tokyo)Masashi Isshiki(The University of Tokyo)Hiroki Yoshida(Japan Science and Technology Agency)Akio Saiura(The University of Tokyo)Miho Isobe(Japan Science and Technology Agency)Taeko Yokochi(The University of Tokyo)Jun‐ichiro Inoue(Tokyo University of Science)Erwin F. Wagner(Research Institute of Molecular Pathology)Tak W. Mak(University of Toronto)Tatsuhiko Kodama(The University of Tokyo)Tadatsugu Taniguchi✉(The University of Tokyo)
Signaling Pathways in DiseaseBone Metabolism and DiseasesNF-κB Signaling PathwaysRANKLCell biologyNFATBiologyTranscription factorOsteoclastCellular differentiationSignal transductionEctopic expressionEmbryonic stem cell
MeSH terms
AnimalsCarrier ProteinsCell DifferentiationCells, CulturedDNA-Binding ProteinsGene Expression RegulationGenetic TestingHematopoietic Stem CellsMembrane GlycoproteinsMice, Inbred C57BLNuclear ProteinsOsteoclastsPromoter Regions, GeneticProteinsRNA, Messenger
Funding
- McGill University
- CYTED Ciencia y Tecnología para el Desarrollo
- Japan Society for the Promotion of Science
Citations
2,657
FWCI
34.93
field-weighted impact
References
65
Percentile
100%
vs. same field & year
Citations per year
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References
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Modulation of Osteoclast Differentiation and Function by the New Members of the Tumor Necrosis Factor Receptor and Ligand Families
Endocrine Reviews · 1999 · 2,264 citations
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Developmental Cell · 2002 · 1,599 citations
Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation
Cell · 1998 · 5,439 citations
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
Proceedings of the National Academy of Sciences · 1998 · 4,244 citations
TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function
Annual Review of Immunology · 1997 · 2,603 citations
Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis*
Endocrine Reviews · 2000 · 2,226 citations
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