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Validity of the MoCA and MMSE in the detection of MCI and dementia in Parkinson disease

Neurology · 2009 · Vol. 73(21) · pp. 1738–1745
Staci HoopsSarra NazemAndrew SiderowfJohn E. DudaSharon X. XieM. B. SternDaniel Weintraub

Abstract

The Montreal Cognitive Assessment, but not the Mini-Mental State Examination, has adequate psychometric properties as a screening instrument for the detection of mild cognitive impairment or dementia in Parkinson disease. However, a positive screen using either instrument requires additional assessment due to suboptimal specificity at the recommended screening cutoff point.

Dementia and Cognitive Impairment ResearchParkinson's Disease Mechanisms and TreatmentsGinkgo biloba and Cashew ApplicationsMontreal Cognitive AssessmentDementiaReceiver operating characteristicMedicineNeuropsychologyConfidence intervalCognitionPsychologyPsychiatryInternal medicine

MeSH terms

AgedCognition DisordersData CollectionDementiaFemaleHumansMaleMental Status ScheduleMiddle AgedNeuropsychological TestsParkinson DiseasePsychometricsRetrospective StudiesSensitivity and SpecificityReproducibility of Results

Funding

  • U.S. Department of Defense
  • U.S. Department of Veterans Affairs
  • Michael J. Fox Foundation for Parkinson's Research
  • Pfizer
  • Sanofi
  • Teva Pharmaceutical Industries
  • Demensförbundet
  • Neuroscience Research Australia
  • ACADIA Pharmaceuticals
  • Supernus Pharmaceuticals
  • Lewy Body Dementia Association
  • Ipsen
  • National Institutes of Health
  • National Institute of Neurological Disorders and Stroke
  • U.S. Army Medical Research Acquisition Activity
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