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Gene Expression Analysis of Human Prostate Carcinoma during Hormonal Therapy Identifies Androgen-Responsive Genes and Mechanisms of Therapy Resistance

American Journal Of Pathology · 2004 · Vol. 164(1) · pp. 217–227
Jeff M. HolzbeierleinPriti LalÉva LatulippeAlex SmithJaya M. SatagopanLiying ZhangCharles J. RyanSteve SmithHoward I. ScherPeter T. ScardinoVictor E. ReuterWilliam L. Gerald
Prostate Cancer Treatment and ResearchUbiquitin and proteasome pathwaysHormonal and reproductive studiesFlutamideAndrogenAndrogen receptorProstate cancerHormonal therapyLNCaPBiologyCancer researchAntiandrogenEndocrinology

MeSH terms

AlgorithmsDrug Therapy, CombinationFlutamideHumansMaleProstatic NeoplasmsGene Expression Regulation, NeoplasticGoserelinIn Situ Hybridization, FluorescenceAntineoplastic Agents, HormonalDrug Resistance, NeoplasmGene Expression ProfilingCell Line, Tumor

Funding

  • National Institutes of Health
Citations
571
FWCI
15.78
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99%
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Citations per year
References
The development of androgen-independent prostate cancer
Nature reviews. Cancer · 2001 · 2,308 citations
Cancer Statistics, 2003
CA A Cancer Journal for Clinicians · 2003 · 3,295 citations
Cluster analysis and display of genome-wide expression patterns
Proceedings of the National Academy of Sciences · 1998 · 16,353 citations
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