review Open AccessTop 1% cited
The Hippo Signaling Pathway in Development and Cancer
Developmental Cell · 2010 · Vol. 19(4) · pp. 491–505
Duojia Pan✉(Howard Hughes Medical Institute)
Hippo pathway signaling and YAP/TAZBiologyHippo signaling pathwaySignal transductionCancerCell biologyCancer researchComputational biologyGenetics
MeSH terms
Hippo KinasesAnimalsDrosophila melanogasterGene Expression RegulationHumansNeoplasmsSignal TransductionProtein Serine-Threonine KinasesTumor Suppressor ProteinsDrosophila ProteinsEmbryonic DevelopmentIntracellular Signaling Peptides and Proteins
Citations
2,278
FWCI
41.91
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References
187
Percentile
100%
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Citations per year
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References
Expression of Yes-associated protein in common solid tumors
Human Pathology · 2008 · 543 citations
The Hippo Signaling Pathway Components Lats and Yap Pattern Tead4 Activity to Distinguish Mouse Trophectoderm from Inner Cell Mass
Developmental Cell · 2009 · 1,063 citations
The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals
Developmental Cell · 2010 · 814 citations
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
Genes & Development · 2007 · 3,113 citations
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF<sup>β-TRCP</sup>
Genes & Development · 2010 · 1,422 citations
TAZ Promotes Cell Proliferation and Epithelial-Mesenchymal Transition and Is Inhibited by the Hippo Pathway
Molecular and Cellular Biology · 2008 · 916 citations
YAP1 Increases Organ Size and Expands Undifferentiated Progenitor Cells
Current Biology · 2007 · 1,265 citations
TEAD mediates YAP-dependent gene induction and growth control
Genes & Development · 2008 · 2,488 citations
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