reviewTop 10% cited

Role of Smads in TGFβ signaling

Cell and Tissue Research · 2011 · Vol. 347(1) · pp. 21–36

Carl‐Henrik Heldin✉(Uppsala University)Aristidis Moustakas(Science for Life Laboratory)

TGF-β signaling in diseases Kruppel-like factors research Cancer-related gene regulationSMADSUMO proteinR-SMADCell biologyPhosphorylationTranscription factorBiologySignal transductionSmad2 ProteinSerine

MeSH terms

AnimalsHumansNeoplasmsProtein Processing, Post-TranslationalSignal TransductionTransforming Growth Factor betaProtein IsoformsActive Transport, Cell NucleusMicroRNAsSmad ProteinsEpithelial-Mesenchymal Transition

Citations

322

FWCI

8.78

field-weighted impact

References

178

Percentile

99%

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References

Mechanism of TGF-β signaling to growth arrest, apoptosis, and epithelial–mesenchymal transition

Current Opinion in Cell Biology · 2009 · 646 citations

Epithelial-Mesenchymal Transitions in Development and Disease

Cell · 2009 · 9,875 citations

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

Nature Cell Biology · 2003 · 1,158 citations

Molecular requirements for epithelial–mesenchymal transition during tumor progression

Current Opinion in Cell Biology · 2005 · 1,816 citations

Smad7 Binds to Smurf2 to Form an E3 Ubiquitin Ligase that Targets the TGFβ Receptor for Degradation

Molecular Cell · 2000 · 1,326 citations

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

Nature reviews. Cancer · 2007 · 3,063 citations

TGF-β Superfamily Signaling in Embryonic Development and Homeostasis

Developmental Cell · 2009 · 734 citations

Non-Smad TGF-β signals

Journal of Cell Science · 2005 · 1,071 citations

Smad regulation in TGF-β signal transduction

Journal of Cell Science · 2001 · 924 citations

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