reviewTop 1% cited
Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
Nature Immunology · 2005 · Vol. 6(4) · pp. 345–352
Shimon Sakaguchi✉(Kyoto University)
T-cell and B-cell ImmunologyImmune Cell Function and InteractionImmunotherapy and Immune ResponsesFOXP3Self ToleranceIL-2 receptorImmunologyImmune toleranceBiologyImmunityAntigenRegulatory T cellPopulation
MeSH terms
AnimalsAntigens, DifferentiationAutoimmune DiseasesDNA-Binding ProteinsHumansLymphocyte ActivationNeoplasmsT-LymphocytesThymus GlandTransplantation ImmunologyReceptors, Interleukin-2Antigens, CDCD4 AntigensSelf ToleranceForkhead Transcription Factors
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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
Nature Genetics · 2001 · 3,333 citations
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