article Open AccessTop 1% cited
Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN
Cancer Cell · 2009 · Vol. 16(3) · pp. 183–194
Zvi G. Fridlender✉(University of Pennsylvania)Jing Sun(University of Pennsylvania)Samuel Kim(University of Pennsylvania)Veena Kapoor(University of Pennsylvania)Guanjun Cheng(University of Pennsylvania)Leona Ling(Biogen (United States))G. Scott Worthen(Children's Hospital of Philadelphia)Steven Μ. Albelda(University of Pennsylvania)
Immune cells in cancerChemokine receptors and signalingNeutrophil, Myeloperoxidase and Oxidative MechanismsPhenotypeCancer researchBiologyImmunologyGeneticsGene
MeSH terms
AnimalsAntigens, LyCell Line, TransformedCell Transformation, ViralImmunohistochemistryLung NeoplasmsMesotheliomaMice, Inbred BALB CMice, Inbred C57BLMice, TransgenicNeutrophilsPhenotypeRNA, MessengerCytokinesTransforming Growth Factor beta
Funding
- National Cancer Institute
- National Institute of Environmental Health Sciences
Citations
3,276
FWCI
25.11
field-weighted impact
References
58
Percentile
100%
vs. same field & year
Citations per year
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References
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Immunological Reviews · 2008 · 636 citations
Myeloid-derived suppressor cells as regulators of the immune system
Nature reviews. Immunology · 2009 · 6,584 citations
The neutrophil as a cellular source of chemokines
Immunological Reviews · 2000 · 797 citations
Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives
Immunological Reviews · 2008 · 692 citations
Gemcitabine Selectively Eliminates Splenic Gr-1+/CD11b+ Myeloid Suppressor Cells in Tumor-Bearing Animals and Enhances Antitumor Immune Activity
Clinical Cancer Research · 2005 · 1,047 citations
Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice
Journal of Leukocyte Biology · 2007 · 1,032 citations
Arginase I Production in the Tumor Microenvironment by Mature Myeloid Cells Inhibits T-Cell Receptor Expression and Antigen-Specific T-Cell Responses
Cancer Research · 2004 · 1,222 citations
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