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Ovarian Conservation at the Time of Hysterectomy and Long-Term Health Outcomes in the Nurses’ Health Study
Obstetrics and Gynecology · 2009 · Vol. 113(5) · pp. 1027–1037
William H. Parker✉(Saint John's Health Center)Michael S. Broder(Partnership for Health Analytic Research)Eunice Chang(Partnership for Health Analytic Research)Diane Feskanich(Brigham and Women's Hospital)Cindy Farquhar(University of Auckland)Zhimae Liu(Cerner (United States))Donna Shoupe(University of Southern California)Jonathan S. Berek(Stanford University)Susan E. Hankinson(Brigham and Women's Hospital)JoAnn E. Manson(Brigham and Women's Hospital)
Abstract
Compared with ovarian conservation, bilateral oophorectomy at the time of hysterectomy for benign disease is associated with a decreased risk of breast and ovarian cancer but an increased risk of all-cause mortality, fatal and nonfatal coronary heart disease, and lung cancer. In no analysis or age group was oophorectomy associated with increased survival.
Endometriosis Research and TreatmentUterine Myomas and TreatmentsEndometrial and Cervical Cancer TreatmentsMedicineOophorectomyHysterectomyHazard ratioStroke (engine)Breast cancerOvarian cancerGynecologyObstetricsUterine cancer
MeSH terms
AdultCardiovascular DiseasesFemaleFollow-Up StudiesHip FracturesHumansHysterectomyMiddle AgedNeoplasmsNursesOvariectomyPostoperative ComplicationsProspective StudiesRisk FactorsSurvival Rate
Citations
621
FWCI
47.45
field-weighted impact
References
29
Percentile
100%
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