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RNA-guided editing of bacterial genomes using CRISPR-Cas systems

Nature Biotechnology · 2013 · Vol. 31(3) · pp. 233–239
Wenyan JiangDavid BikardDavid CoxFeng ZhangLuciano A. Marraffini
CRISPR and Genetic EngineeringRNA and protein synthesis mechanismsBacterial Genetics and BiotechnologyCRISPRCas9Trans-activating crRNABiologyRecombineeringGenome editingGuide RNARNAComputational biologyBacterial genome size

MeSH terms

Base SequenceEndonucleasesEscherichia coliGenetic EngineeringMolecular Sequence DataStreptococcus pneumoniaeMutagenesis, Site-DirectedGenome, BacterialDNA CleavageRNA, Small Untranslated
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