review Open AccessTop 1% cited
The RB and p53 pathways in cancer
Cancer Cell · 2002 · Vol. 2(2) · pp. 103–112
Charles J. Sherr✉(Howard Hughes Medical Institute)Frank McCormick(University of California, San Francisco)
Cancer-related Molecular PathwaysRetinoids in leukemia and cellular processesOcular Oncology and TreatmentsRetinoblastomaSuppressorCancer researchBiologyTranscription factorCancer cellCancerRetinoblastoma proteinSignal transductionCell biology
MeSH terms
Cell CycleDNA-Binding ProteinsHumansNeoplasmsTranscription FactorsSignal TransductionTumor Suppressor Protein p53Retinoblastoma ProteinApoptosisCell Cycle ProteinsCyclin-Dependent Kinase Inhibitor p16E2F Transcription Factors
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1,658
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References
p53, the Cellular Gatekeeper for Growth and Division
Cell · 1997 · 7,678 citations
The Hallmarks of Cancer
Cell · 2000 · 28,385 citations
The regulation of E2F by pRB-family proteins
Genes & Development · 1998 · 2,307 citations
Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a
Cell · 1997 · 5,018 citations
Safety and antitumor activity of recombinant soluble Apo2 ligand
Journal of Clinical Investigation · 1999 · 2,210 citations
The p21Cip1 and p27Kip1 CDK `inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts
The EMBO Journal · 1999 · 1,141 citations
CDK inhibitors: positive and negative regulators of G1-phase progression
Genes & Development · 1999 · 6,077 citations
The Rb/E2F pathway and cancer
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