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Mitochondrial damage induced by conditions of oxidative stress

Free Radical Biology and Medicine · 1999 · Vol. 26(3-4) · pp. 463–471
Alicia J. KowaltowskiAnı́bal E. Vercesi
Mitochondrial Function and PathologyCoenzyme Q10 studies and effectsMetabolism and Genetic DisordersReactive oxygen speciesOxidative stressSuperoxideMitochondrionHydrogen peroxideChemistryMitochondrial respiratory chainOxygenHydroxyl radicalMitochondrial ROS

MeSH terms

AnimalsDNA DamageDNA, MitochondrialElectron TransportHumansMembrane ProteinsMitochondriaNecrosisOxidation-ReductionPermeabilityLipid PeroxidationApoptosisReactive Oxygen SpeciesOxidative Stress

Funding

  • Fundação de Amparo à Pesquisa do Estado de São Paulo
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References
The Ca2+-induced membrane transition in mitochondria
Archives of Biochemistry and Biophysics · 1979 · 848 citations
Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria
Archives of Biochemistry and Biophysics · 1985 · 1,200 citations
Protein Oxidation in Aging, Disease, and Oxidative Stress
Journal of Biological Chemistry · 1997 · 3,306 citations
Lipid peroxidation: its mechanism, measurement, and significance
American Journal of Clinical Nutrition · 1993 · 2,341 citations
Hydroperoxide metabolism in mammalian organs.
Physiological Reviews · 1979 · 5,812 citations
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