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An Outcome Prediction Model for Patients with Clear Cell Renal Cell Carcinoma Treated with Radical Nephrectomy Based on Tumor Stage, Size, Grade and Necrosis: The Ssign Score

The Journal of Urology · 2002 · Vol. 168(6) · pp. 2395–2400

Igor Frank✉(Mayo Clinic in Florida)Michael L. Blute(Mayo Clinic in Florida)John C. Cheville(Mayo Clinic in Florida)Christine M. Lohse(Mayo Clinic in Florida)Amy L. Weaver(Mayo Clinic in Florida)Horst Zincke(Mayo Clinic in Florida)

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Abstract

In patients with clear cell renal cell carcinoma 1997 TNM stage, tumor size, nuclear grade and histological tumor necrosis were significantly associated with cancer specific survival. We present a scoring system based on these features that can be used to predict outcome.

Renal cell carcinoma treatment Renal and related cancers Multiple and Secondary Primary CancersMedicineNephrectomyRenal cell carcinomaStage (stratigraphy)Clear cell renal cell carcinomaPathologicalPathologyUrologyInternal medicineOncology

MeSH terms

AdultAgedAged, 80 and overAlgorithmsCarcinoma, Renal CellFemaleHumansKidney NeoplasmsMaleMiddle AgedNecrosisNeoplasm StagingNephrectomyRisk FactorsSmoking

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Histopathological aspects of adult renal tumors at tertiary care center