article Open AccessTop 1% cited
Estimating Missing Heritability for Disease from Genome-wide Association Studies
The American Journal of Human Genetics · 2011 · Vol. 88(3) · pp. 294–305
Sang Lee✉(QIMR Berghofer Medical Research Institute)Naomi R. Wray(QIMR Berghofer Medical Research Institute)Michael E. Goddard(The University of Melbourne)Peter M. Visscher(QIMR Berghofer Medical Research Institute)
Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestockLiver Disease Diagnosis and TreatmentHeritabilityMissing heritability problemGenome-wide association studyGenetic associationAssociation (psychology)DiseaseMissing dataBiologyGeneticsMedicine
MeSH terms
Bipolar DisorderComputer SimulationCrohn DiseaseDiabetes Mellitus, Type 1DiseaseHumansModels, GeneticQuality ControlGenetic VariationCase-Control StudiesPolymorphism, Single NucleotideInheritance PatternsGenome-Wide Association Study
Funding
- Wellcome Trust
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- Australian Research Council
- National Health and Medical Research Council
- National Human Genome Research Institute
Citations
1,160
FWCI
53.40
field-weighted impact
References
36
Percentile
100%
vs. same field & year
Citations per year
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References
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Nature Reviews Genetics · 2008 · 1,936 citations
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Nature · 2007 · 9,601 citations
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Common SNPs explain a large proportion of the heritability for human height
Nature Genetics · 2010 · 4,788 citations
Principal components analysis corrects for stratification in genome-wide association studies
Nature Genetics · 2006 · 10,603 citations
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