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Prognostic value of blood pressure in patients with high vascular risk in the Ongoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial study

Journal of Hypertension · 2009 · Vol. 27(7) · pp. 1360–1369
Peter SleightJosep RedónPaolo VerdecchiaGiuseppe ManciaPeggy GaoRobert FagardHelmut SchumacherMichael A. WeberMichael BöhmBryan WilliamsJanice PogueKoon TeoSalim Yusuf

Abstract

In high-risk patients, the benefits from SBP lowering below 130 mmHg are driven mostly by a reduction of stroke; myocardial infarction is unaffected and cardiovascular mortality is unchanged or increased. Future trials should be designed to test the value of SBP lowering in high-risk patients with SBP in the range of 130-150 mmHg.

Blood Pressure and Hypertension StudiesCardiovascular Health and Disease PreventionHormonal Regulation and HypertensionMedicineRamiprilTelmisartanBlood pressureInternal medicineMyocardial infarctionStroke (engine)CardiologyDiabetes mellitusClinical endpoint

MeSH terms

TelmisartanAgedAngiotensin-Converting Enzyme InhibitorsAntihypertensive AgentsBenzimidazolesBenzoatesBlood PressureDouble-Blind MethodFemaleHumansHypertensionMaleMiddle AgedPrognosisTreatment Outcome
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