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Diabetes and Cancer: A Consensus Report

CA A Cancer Journal for Clinicians · 2010 · Vol. 60(4) · pp. 207–221

Edward L. Giovannucci✉(Harvard University)David M. Harlan(University of Massachusetts Chan Medical School)Michael C. Archer(University of Toronto)Richard M. Bergenstal(Park Nicollet Clinic)Susan M. Gapstur(American Cancer Society)Laurel A. Habel(Kaiser Permanente)Michaël Pollak(McGill University)Judith G. Regensteiner(University of Colorado Denver)Douglas Yee(University of Minnesota)

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Abstract

Epidemiologic evidence suggests that cancer incidence is associated with diabetes as well as certain diabetes risk factors and treatments. This consensus statement of experts assembled jointly by the American Diabetes Association and the American Cancer Society reviews the state of science concerning 1) the association between diabetes and cancer incidence or prognosis; 2) risk factors common to both diabetes and cancer; 3) possible biologic links between diabetes and cancer risk; and 4) whether diabetes treatments influence the risk of cancer or cancer prognosis. In addition, key unanswered questions for future research are posed.

Metabolism, Diabetes, and Cancer Diabetes Treatment and Management Pancreatic and Hepatic Oncology ResearchDiabetes mellitusMedicineCancerIncidence (geometry)Cancer incidenceGerontologyFamily medicineIntensive care medicineInternal medicineEndocrinology

MeSH terms

Age FactorsAlcohol DrinkingDiabetes MellitusDietEstrogensHumansHyperglycemiaHyperinsulinismHypoglycemic AgentsInsulinMetforminMotor ActivityNeoplasmsReceptor, InsulinRisk Factors

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