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Risk Factors and Causes of Death in MEN1 Disease. A GTE (Groupe d’Etude des Tumeurs Endocrines) Cohort Study Among 758 Patients

World Journal of Surgery · 2009 · Vol. 34(2) · pp. 249–255
Pierre GoudetArnaud MuratChristine BinquetC. Cardot‐BautersAnnie CostaPhilippe RuszniewskiPatricia NiccoliFabrice MènégauxG ChabrierFrançoise Borson‐ChazotAntoine TabarinPhilippe BouchardBrigitte DelemerAlbert BeckersClaire Bonithon‐Kopp

Abstract

The prognosis of MEN1 disease has improved since 1980. Thymic tumors and duodenopancreatic tumors, including nonsecreting pancreatic tumors, increased the risk of death. Rare but aggressive adrenal tumors may also cause death. Most deaths were related to MEN1. New recommendations on abdominal and thoracic imaging are required.

Neuroendocrine Tumor Research AdvancesLung Cancer Research StudiesNeuroblastoma Research and TreatmentsMEN1MedicineMultiple endocrine neoplasiaGastrinomaHazard ratioInternal medicineCohortNeuroendocrine tumorsDiseaseCause of death

MeSH terms

AdultBelgiumCause of DeathDiagnostic ImagingFemaleFollow-Up StudiesFranceHumansMaleMiddle AgedPrognosisRisk FactorsChi-Square DistributionProportional Hazards ModelsSurvival Analysis
Citations
338
FWCI
7.60
field-weighted impact
References
37
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98%
vs. same field & year
Citations per year
Cited by
Clinical Practice Guidelines for Multiple Endocrine Neoplasia Type 1 (MEN1)
The Journal of Clinical Endocrinology & Metabolism · 2012 · 1,439 citations
Multiple endocrine neoplasia type 1 (MEN1) and type 4 (MEN4)
Molecular and Cellular Endocrinology · 2013 · 425 citations
References
Genetic aspects of adenomatosis of endocrine glands
The American Journal of Medicine · 1954 · 865 citations
CONSENSUS: Guidelines for Diagnosis and Therapy of MEN Type 1 and Type 2
The Journal of Clinical Endocrinology & Metabolism · 2001 · 1,900 citations
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