articleTop 1% cited

Rab27a and Rab27b control different steps of the exosome secretion pathway

Nature Cell Biology · 2009 · Vol. 12(1) · pp. 19–30

Matías Ostrowski✉(Inserm)Nuno Carmo(Hospital de Egas Moniz)Sophie Krumeich(Inserm)Isabelle Fanget(Institut de Biologie Physico-Chimique)Graça Raposo(Centre National de la Recherche Scientifique)Ariel Savina(Inserm)Catarina Moita(Hospital de Egas Moniz)Kristine Schauer(Centre National de la Recherche Scientifique)Alistair N. Hume(Imperial College London)Rui Freitas(Hospital de Egas Moniz)Bruno Goud(Centre National de la Recherche Scientifique)Philippe Benaroch(Inserm)Nir Hacohen(Broad Institute)Mitsunori Fukuda(Tohoku University)Claire Desnos(Institut de Biologie Physico-Chimique)Miguel C. Seabra(Imperial College London)François Darchen(Institut de Biologie Physico-Chimique)Sebastián Amigorena(Inserm)Luís F. Moita(Hospital de Egas Moniz)Clotilde Théry(Inserm)

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Extracellular vesicles in disease Cellular transport and secretion RNA Interference and Gene DeliveryRabExosomeCell biologySecretionMicrovesiclesEndosomeGene silencingEffectorBiologyRNA interference

MeSH terms

rab27 GTP-Binding ProteinsCell CommunicationCell MembraneFlow CytometryFluorescent Antibody TechniqueHeLa CellsHumansEndosomesRNA, MessengerSubcellular FractionsImmunoblottingReverse Transcriptase Polymerase Chain Reactionrab GTP-Binding ProteinsGene SilencingVesicular Transport Proteins

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