reviewTop 10% cited
Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation
Psychopharmacology · 1997 · Vol. 134(4) · pp. 319–329
Paul Willner✉(Swansea University)
Tryptophan and brain disordersStress Responses and CortisolNeurotransmitter Receptor Influence on BehaviorAnhedoniaFace validityStressorPsychologyAnimal models of depressionDepression (economics)Construct validityPredictive validityChronic stressAnimal model
MeSH terms
AnimalsChronic DiseaseDepressive DisorderDisease Models, AnimalStress, PsychologicalReproducibility of ResultsMiceRats
Citations
1,809
FWCI
7.23
field-weighted impact
References
63
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98%
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References
THE BIOLOGY OF HUMAN STARVATION
The Medical Journal of Australia · 1951 · 2,060 citations
Acute and chronic stress effects on open field activity in the rat: Implications for a model of depression
Neuroscience & Biobehavioral Reviews · 1981 · 874 citations
The validity of animal models of depression
Psychopharmacology · 1984 · 1,391 citations
An animal model of anhedonia: attenuation of sucrose consumption and place preference conditioning by chronic unpredictable mild stress
Psychopharmacology · 1991 · 527 citations
Chronic mild stress-induced anhedonia: A realistic animal model of depression
Neuroscience & Biobehavioral Reviews · 1992 · 1,147 citations
Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant
Psychopharmacology · 1987 · 1,948 citations
Animal model of depression: Pharmacological sensitivity of a hedonic deficit
Pharmacology Biochemistry and Behavior · 1982 · 469 citations
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