article Open AccessTop 1% cited
Superoxide is the major reactive oxygen species regulating autophagy
Cell Death and Differentiation · 2009 · Vol. 16(7) · pp. 1040–1052
Yongqiang Chen✉(University of Manitoba)Meghan B. Azad(University of Manitoba)Spencer B. Gibson(University of Manitoba)
Autophagy in Disease and TherapyAutophagyReactive oxygen speciesProgrammed cell deathChemistryIntracellularSuperoxideSuperoxide dismutaseBiochemistryHydrogen peroxideMitochondrion
MeSH terms
Beclin-1Autophagy-Related Protein 72-MethoxyestradiolAntioxidantsAutophagyCatalaseCell LineEstradiolHeLa CellsHumansHydrogen PeroxideMembrane ProteinsMicrotubule-Associated ProteinsSuperoxidesSuperoxide Dismutase
Funding
- U.S. Department of Defense
- Manitoba Health Research Council
- CancerCare Manitoba Foundation
Citations
788
FWCI
20.57
field-weighted impact
References
34
Percentile
100%
vs. same field & year
Citations per year
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References
The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy
Biochimica et Biophysica Acta (BBA) - Bioenergetics · 1998 · 1,382 citations
Oxidative stress and apoptosis: Impact on cancer therapy
Journal of Pharmaceutical Sciences · 2007 · 740 citations
Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells
Cell Death and Differentiation · 2007 · 682 citations
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
The EMBO Journal · 2007 · 2,074 citations
Autophagy in cell death: an innocent convict?
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