article Open AccessTop 1% cited

MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells

Nature Methods · 2007 · Vol. 4(9) · pp. 721–726

Margaret S. Ebert✉Joel R. Neilson(Massachusetts Institute of Technology)Phillip A. Sharp(Center for Cancer Research)

MicroRNA in disease regulation Advanced biosensing and bioanalysis techniques RNA Interference and Gene DeliverymicroRNABiologyOligonucleotideTransfectionGeneSpongeRNACell sortingGene silencingReporter gene

MeSH terms

AnimalsGenetic VectorsHeLa CellsHumansPlasmidsRNA Polymerase IIITransfectionBlotting, NorthernBlotting, WesternOligonucleotides, AntisenseGenes, Reporter3' Untranslated RegionsRNA InterferenceMicroRNAsLuciferases, Firefly

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