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Antigenic Relationships between Flaviviruses as Determined by Cross-neutralization Tests with Polyclonal Antisera

Journal of General Virology · 1989 · Vol. 70(1) · pp. 37–43

Charles H. Calisher✉(United States Department of Health and Human Services)Nick Karabatsos(United States Department of Health and Human Services)Joel M. Dalrymple(United States Army Medical Research Institute of Infectious Diseases)R. E. ShopeJ. S. Porterfield(University of Oxford)E. G. Westaway(Monash University)Walter E. Brandt

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Abstract

The recently established virus family Flaviviridae contains at least 68 recognized members. Sixty-six of these viruses were tested by cross-neutralization in cell cultures. Flaviviruses were separated into eight complexes [tick-borne encephalitis (12 viruses), Rio Bravo (six), Japanese encephalitis (10), Tyuleniy (three), Ntaya (five), Uganda S (four), dengue (four) and Modoc (five)] containing 49 viruses; 17 other viruses were not sufficiently related to warrant inclusion in any of these complexes.

Mosquito-borne diseases and control Viral Infections and Vectors Malaria Research and ControlVirologyNeutralizationBiologyDengue feverJapanese encephalitisAntiserumFlaviviridaeFlavivirusPolyclonal antibodiesEncephalitis