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Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

Nature Cell Biology · 2008 · Vol. 10(5) · pp. 619–624
Khalid Al‐NedawiBrian MeehanJohann MicallefVladimir LhotakLinda MayAbhijit GuhaJanusz Rak
Extracellular vesicles in diseaseRNA Research and SplicingRNA Interference and Gene DeliveryMicrovesiclesCell biologyBiologyGliomaCancer cellEpidermal growth factor receptorPhenotypeReceptorChemistryCancer research

MeSH terms

AnimalsCell MembraneGliomaHumansMembrane ProteinsRecombinant Fusion ProteinsTumor Cells, CulturedSignal TransductionMembrane MicrodomainsTransport VesiclesMiceErbB Receptors

Funding

  • McGill University
  • Pfizer Canada
  • Canadian Institutes of Health Research
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