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Mortality among regular or dependent users of heroin and other opioids: a systematic review and meta-analysis of cohort studies

Addiction · 2010 · Vol. 106(1) · pp. 32–51
Louisa DegenhardtChiara BucelloBradley MathersChristina BrieglebHammad AliMatthew HickmanJennifer McLaren

Abstract

Mortality among opioid-dependent users varies across countries and populations. Treatment is clearly protective against mortality even in non-randomized observational studies. Study characteristics predict mortality levels; these should be taken into account in future studies.

Opioid Use Disorder TreatmentPrenatal Substance Exposure EffectsSubstance Abuse Treatment and OutcomesMedicineObservational studyDemographyMeta-analysisMortality rateEpidemiologyCohort studyPsycINFOMEDLINESelection bias

MeSH terms

AdultAnalgesics, OpioidAsiaCause of DeathEuropeFemaleHumansMaleOpioid-Related DisordersNorth AmericaRecurrenceTime FactorsHIV InfectionsSubstance Abuse, IntravenousAustralasia
Citations
856
FWCI
29.16
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References
87
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100%
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