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Peripheral opioid receptors mediating antinociception in inflammation. Evidence for involvement of mu, delta and kappa receptors.

Journal of Pharmacology and Experimental Therapeutics · 1989 · Vol. 248(3) · pp. 1269–1275
Christoph SteinM J MillanToni S. ShippenbergKarlheinz PeterA. Herz
Neuropeptides and Animal PhysiologyCancer, Stress, Anesthesia, and Immune ResponsePharmacological Receptor Mechanisms and EffectsOpioidReceptorμ-opioid receptorEnkephalinκ-opioid receptorChemistryPharmacology(+)-Naloxoneδ-opioid receptorMorphine

MeSH terms

AnalgesiaAnimalsDose-Response Relationship, DrugEnkephalinsInflammationMaleNaloxonePyrrolidinesRats, Inbred StrainsReceptors, OpioidSensory ThresholdsReceptors, Opioid, muReceptors, Opioid, deltaReceptors, Opioid, kappa3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer
Citations
528
FWCI
5.61
field-weighted impact
References
0
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98%
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