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Global Morbidity and Mortality of Leptospirosis: A Systematic Review

PLoS neglected tropical diseases · 2015 · Vol. 9(9) · pp. e0003898–e0003898
Federico CostaJosé E. HaganJuan Ignácio CalcagnoMichael J. KanePaul R. TorgersonMartha Sílvia Martinez-SilveiraCláudia SteinBernadette Abela-RidderAlbert I. Ko

Abstract

Leptospirosis is among the leading zoonotic causes of morbidity worldwide and accounts for numbers of deaths, which approach or exceed those for other causes of haemorrhagic fever. Highest morbidity and mortality were estimated to occur in resource-poor countries, which include regions where the burden of leptospirosis has been underappreciated.

Leptospirosis research and findingsViral Infections and VectorsZoonotic diseases and public healthMedicineDemographyLife expectancyEpidemiologyPopulationIncidence (geometry)Case fatality rateMortality rateDisease burdenDisease

MeSH terms

Age FactorsAnimalsHumansLeptospirosisMortalitySex FactorsGlobal HealthZoonosesIncidenceSurvival AnalysisNeglected Diseases

Funding

  • World Health Organization
  • Wellcome Trust
  • Ministério da Educação
  • National Institutes of Health
Citations
1,901
FWCI
74.18
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