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The Efficacy of Disulfiram for the Treatment of Alcohol Use Disorder
Alcoholism Clinical and Experimental Research · 2011 · Vol. 35(10) · pp. 1749–1758
Abstract
Supervised treatment with disulfiram has some effect on short-term abstinence and days until relapse as well as number of drinking days when compared with placebo, none, or other treatments for patients with alcohol dependency or abuse. Long-term effect on abstinence has not been evaluated yet. However, there is a need for more homogeneous and high-quality studies in the future regarding the efficacy of disulfiram.
Substance Abuse Treatment and OutcomesAlcohol Consumption and Health EffectsCannabis and Cannabinoid ResearchDisulfiramAbstinenceMedicinePlaceboAcamprosateAlcohol dependenceInternal medicineMeta-analysisAlcoholAlcohol use disorder
MeSH terms
AdolescentAdultAgedAlcohol DeterrentsEthanolAlcoholismCentral Nervous System DepressantsDisulfiramFemaleHumansMaleMiddle AgedAlcohol-Related DisordersSecondary PreventionYoung Adult
Citations
364
FWCI
10.38
field-weighted impact
References
39
Percentile
99%
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Citations per year
References
Efficacy and safety of naltrexone and acamprosate in the treatment of alcohol dependence: a systematic review
Addiction · 2004 · 508 citations
Measuring inconsistency in meta-analyses
BMJ · 2003 · 61,700 citations
The Efficacy of Acamprosate in the Maintenance of Abstinence in Alcohol‐Dependent Individuals: Results of a Meta‐Analysis
Alcoholism Clinical and Experimental Research · 2004 · 363 citations
Effectiveness of brief alcohol interventions in primary care populations
Cochrane Database of Systematic Reviews · 2018 · 1,662 citations
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