articleTop 1% cited
Colonic bacterial composition in Parkinson's disease
Movement Disorders · 2015 · Vol. 30(10) · pp. 1351–1360
Ali Keshavarzian✉(Utrecht University)Stefan J. Green(University of Illinois Chicago)Phillip A. Engen(Rush University Medical Center)Robin M. Voigt(Rush University Medical Center)Ankur Naqib(University of Illinois Chicago)Christopher B. Forsyth(Rush University Medical Center)Ece Mutlu(Rush University Medical Center)Kathleen M. Shannon(Rush University Medical Center)
Abstract
This report provides evidence that proinflammatory dysbiosis is present in PD patients and could trigger inflammation-induced misfolding of α-Syn and development of PD pathology.
Parkinson's Disease Mechanisms and TreatmentsGut microbiota and healthDysphagia Assessment and ManagementDysbiosisRoseburiaBiologyPrevotellaProteobacteriaMicrobiologyProinflammatory cytokineGut floraFecesMicrobiome
MeSH terms
AdultAgedFecesFemaleHumansIntestinal MucosaMaleMiddle AgedParkinson DiseaseColon, SigmoidProtein Foldingalpha-SynucleinMicrobiotaDysbiosis
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