review Open AccessTop 1% cited
Interleukin-6 and the acute phase response
Biochemical Journal · 1990 · Vol. 265(3) · pp. 621–636
Peter C. Heinrich✉José V. Castell(Instituto de Investigación Sanitaria La Fe)Tilo Andus(University Medical Center Freiburg)
Abstract
ACTH Acutephas specific receptors on different target cells leading to a Corsol proteins systemic reaction characterized by fever, leukocytosis, increase in erythrocyte sedimentation rate, increases in Leucocytosis secretion of ACTH and glucocorticoids, activation of Complement activat
Immune Response and InflammationImmune Cell Function and InteractionCytokine Signaling Pathways and InteractionsIconCitationLibrary scienceDownloadComputer scienceInformation retrievalHumanitiesWorld Wide WebArt
MeSH terms
Acute-Phase ProteinsAcute-Phase ReactionAnimalsBase SequenceHumansInflammationLiverMolecular Sequence DataProteinsTumor Necrosis Factor-alphaSignal TransductionInterleukin-6Rats
Citations
2,757
FWCI
38.49
field-weighted impact
References
229
Percentile
100%
vs. same field & year
Citations per year
Cited by
Elevated C-Reactive Protein
Arteriosclerosis Thrombosis and Vascular Biology · 2001 · 591 citations
Inflammation, immunoregulation, and inducible nitric oxide synthase
Journal of Leukocyte Biology · 1993 · 870 citations
M2b macrophage polarization and its roles in diseases
Journal of Leukocyte Biology · 2018 · 843 citations
Visceral Fat Adipokine Secretion Is Associated With Systemic Inflammation in Obese Humans
Diabetes · 2007 · 1,380 citations
The organization of the stress system and its dysregulation in depressive illness
Molecular Psychiatry · 2014 · 629 citations
C-Reactive Protein in Healthy Subjects: Associations With Obesity, Insulin Resistance, and Endothelial Dysfunction
Arteriosclerosis Thrombosis and Vascular Biology · 1999 · 2,458 citations
Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications
Physiological Reviews · 2006 · 2,261 citations
Circulating markers of inflammation and atherosclerosis
Atherosclerosis · 2003 · 372 citations
References
Interleukin‐6 is the major regulator of acute phase protein synthesis in adult human hepatocytes
FEBS Letters · 1989 · 891 citations
Excessive production of interleukin 6/B cell stimulatory factor‐2 in rheumatoid arthritis
European Journal of Immunology · 1988 · 789 citations
On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases
European Journal of Immunology · 1989 · 686 citations
THE PHENOMENON OF THE ACUTE PHASE RESPONSE*
Annals of the New York Academy of Sciences · 1982 · 1,500 citations
Production of hybridoma growth factor by human monocytes
European Journal of Immunology · 1987 · 1,114 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
