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Vero response to a cytotoxin of Escherichia coli

Infection and Immunity · 1977 · Vol. 18(3) · pp. 775–779

Abstract

A cytotoxin was found in culture filtrates of a number of Escherichia coli strains that differed from the known heat-stable and heat-labile enterotoxins of E. coli. It was cytotoxic for Vero but not for Y-1 or CHO cells, and its effect on Vero was distinctly different from that of heat-labile enterotoxin. It was labile to heat and antigenically different from heat-labile enterotoxin, and membrane filtration indicated a molecular weight of 10,000 to 30,000.

Escherichia coli research studiesBacteriophages and microbial interactionsBacterial Genetics and BiotechnologyVero cellEnterotoxinEscherichia coliBiologyMicrobiologyHeat-stable enterotoxinHeat-labile enterotoxinEscherichia coli ProteinsEnterobacteriaceaeToxin

MeSH terms

Antigens, BacterialBacterial ToxinsCell LineCytotoxinsEscherichia coliHot TemperatureMolecular WeightNeutralization Tests
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