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PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene.

The EMBO Journal · 1996 · Vol. 15(19) · pp. 5336–5348

Kristina Schoonjans✉(Inserm)Julia Peinado‐Onsurbe(Inserm)Anne‐Marie Lefebvre(Inserm)R A Heyman(Inserm)Michael R. Briggs(Inserm)S S Deeb(Inserm)Bart Staels(Inserm)Johan Auwerx(Inserm)

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Peroxisome Proliferator-Activated Receptors Lipid metabolism and disorders Nuclear Receptors and SignalingRose (mathematics)BiologyHumanitiesArt

MeSH terms

RosiglitazoneAdipose TissueAnimalsHypolipidemic AgentsCell LineDNAHumansHypoglycemic AgentsLipoprotein LipaseLiverMice, Inbred C57BLMyocardiumOrgan SpecificityFenofibratePromoter Regions, Genetic

Citations

1,176

FWCI

12.77

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99%

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References

Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids.

Molecular Endocrinology · 1992 · 457 citations

An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

Journal of Biological Chemistry · 1995 · 3,617 citations

Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat.

Endocrinology · 1996 · 2,146 citations

Dietary influences on serum lipids and lipoproteins.

Journal of Lipid Research · 1990 · 1,049 citations

mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer.

Genes & Development · 1994 · 2,174 citations

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