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Granules of the Human Neutrophilic Polymorphonuclear Leukocyte
Blood · 1997 · Vol. 89(10) · pp. 3503–3521
Niels Borregaard✉(Copenhagen University Hospital)Jack B. Cowland(Copenhagen University Hospital)
Abstract
POLYMORPHONUCLEAR leukocytes were discovered by Paul Ehrlich,[1][1] when fixation and staining techniques made it possible to identify the lobulated nucleus and the granules that have given name to these cells and allowed for their classification as eosinophils, basophils, and neutrophils.
Immune Response and InflammationImmune Cell Function and InteractionBlood disorders and treatmentsPolymorphonuclear leukocyteEosinophilGranulocyteStainingImmunologyPathologyAzurophilic granuleNeutrophileGranule (geology)Chemistry
MeSH terms
Biological TransportBlood ProteinsCell CompartmentationCytoplasmic GranulesCytotoxicity, ImmunologicEnzymesExocytosisGene Expression RegulationGolgi ApparatusHumansIntracellular MembranesMembrane FusionNeutrophilsTranscription FactorsTranscription, Genetic
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The Human Gene <i>FALL39</i> and Processing of the Cathelin Precursor to the Antibacterial Peptide LL‐37 in Granulocytes
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