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Clinical trial: vitamin D3 treatment in Crohn’s disease – a randomized double‐blind placebo‐controlled study

Alimentary Pharmacology & Therapeutics · 2010 · Vol. 32(3) · pp. 377–383
Søren Peter JørgensenJørgen AgnholtHenning GlerupSøren LyhneGerda Elisabeth VilladsenChristian Lodberg HvasLars Erik BartelsJens KelsenLisbet Ambrosius ChristensenJens Frederik Dahlerup

Abstract

Oral supplementation with 1200 IE vitamin D3 significantly increased serum vitamin D levels and insignificantly reduced the risk of relapse from 29% to 13%, (P = 0.06). Given that vitamin D3 treatment might be effective in Crohn's disease, we suggest larger studies to elucidate this matter further. ClinicalTrial.gov(NCT00122184).

Microscopic ColitisVitamin D Research StudiesInflammatory Bowel DiseaseMedicinePlaceboCrohn's diseaseVitamin D and neurologyInternal medicineGastroenterologyVitaminCholecalciferolClinical endpointRandomized controlled trial

MeSH terms

CholecalciferolCrohn DiseaseDouble-Blind MethodHumansRecurrenceVitaminsTreatment Outcome

Funding

  • Hørslev-Fonden
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