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Meaningful Change and Responsiveness in Common Physical Performance Measures in Older Adults

Journal of the American Geriatrics Society · 2006 · Vol. 54(5) · pp. 743–749
Subashan PereraSamir H. ModyRichard C. WoodmanStephanie A. Studenski

Abstract

Best initial estimates of small meaningful change are near 0.05 m/s for gait speed, 0.5 points for SPPB, and 20 m for 6MWD and of substantial change are near 0.10 m/s for gait speed, 1.0 point for SPPB, and 50 m for 6MWD. For clinical use, substantial change in these measures and small change in gait speed and 6MWD, but not SPPB, are detectable. For research use, these measures yield feasible sample sizes for detecting meaningful change.

Stroke Rehabilitation and RecoveryBalance, Gait, and Falls PreventionCerebral Palsy and Movement DisordersMedicineGaitPhysical medicine and rehabilitationStroke (engine)Observational studyPreferred walking speedClinical trialPhysical therapyGerontology

MeSH terms

Stroke RehabilitationAgedAged, 80 and overExercise TestFemaleGaitHumansMaleMiddle AgedPsychomotor PerformanceCohort StudiesWalkingRecovery of FunctionStrokeMobility Limitation

Funding

  • U.S. Department of Veterans Affairs
  • Eli Lilly and Company
  • Teva Pharmaceutical Industries
  • National Institute on Aging
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